The illustration is from a liver biopsy of a 34-year-old woman with a long history of alcoholism. Which of the following is the best explanation for the changes shown here?

A) Accumulation of triglycerides within hepatocytes
B) Apoptosis with replacement of damaged cells by lipid laden macrophages
C) Bilirubin accumulation with mobilization of fat by bile salts
D) Enzymatic fat necrosis with digestion of liver parenchyma by released enzymes
E) Irreversible damage to mitochondria

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