A hyperthyroid patient came with complaints over his shin region. The photograph was taken and is displayed here. True statement about this condition is ?

A hyperthyroid patient came with complaints over his shin region. The photograph was taken and is displayed here. True statement about this condition is ?

  1. Also known as pretibial myxedema
  2. It is always seen in the presence of moderate or severe ophthalmopathy
  3. Known as “orange skin” appearance
  4. All of the above

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